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IVF Trigger Injection

IVF Trigger Injection

Aspiring parenthood through IVF treatment involves several processes that couples have to pass through. One such process is taking trigger shots as part of the medication regimen. The trigger shot, which contains the hormone hCG is administered to stimulate a natural surge in ovulation, prompting the final maturation and release of eggs from ovaries. In this article, let’s explore further about the procedures and benefits of IVF trigger injection. Keep reading!

What does the Trigger Shot do in IVF?

In IVF treatment, several injections are administered to increase the success of the process, with the trigger injection being one of the most important. The most critical aspect we cannot control is hormone production. We try to simulate hormones and artificially trigger ovulation to facilitate egg retrieval at the right time – hence, the trigger injection (hormonal injection). It contains Human Chorionic Gonadotropin (the hormone of pregnancy), which mimics the Luteinizing Hormone secreted by the pituitary gland, helping the eggs mature and triggering ovulation.

As the name suggests, the trigger injection finalizes the maturation of eggs and stimulates their release from the follicles. It is typically given 36 hours before the egg retrieval procedure.

Types of Trigger Injections

There are many types of trigger injections used in IVF treatment including:

hCG (Human Chorionic Gonadotropin) trigger: hCG is produced naturally in placenta to support pregnancy. In IVF, it is produced in the laboratory and injected as a shot to help women with inconsistent ovulation and hormonal imbalance. It effectively stimulates the egg maturation and ovulation as like natural Luteinizing hormone (LH). After the hCG injection, women may experience symptoms of egg rupture, such as mild abdominal discomfort or bloating, which indicates that the eggs are maturing and getting ready for retrieval.

Lupron trigger:The release of LH naturally occurs in the body during a menstrual cycle. However, if the hormone secretion is not proper in one body, then it is being regulated artificially by using medications. Medications such as Lupron belong to the class of GnRH agonists which is administered through a shot. This will stimulate the secretion and release of LH of the pituitary gland in order to induce ovulation.

What happens after the Trigger Shot in IVF?

Once you receive the trigger shot, the eggs mature fully within about 36 hours. This precise timing is essential because it aligns with the egg retrieval procedure, which is scheduled shortly after the shot is administered. The trigger shot helps to ensure that the eggs are at their optimal stage for retrieval and fertilization.

Who gets the Trigger Shot?

The trigger shot is given to women who are having their eggs retrieved, such as those using their own eggs, donating eggs, or using previously frozen eggs. However, it is not typically given to men, women using donor eggs without egg retrieval process, or women undergoing embryo transfer only. The treatment procedure is determined only by fertility specialists as individual health conditions may vary.

Why is the Trigger Shot necessary in IVF Treatment?

Here are the reasons why trigger shot is necessary in IVF treatment:

  • Helps eggs mature and get released
  • Ensures ovulation happen at the right time
  • Gives the best quality eggs for better fertilisation chances
  • Make the egg collection process easier
  • Increase the effectiveness of IVF treatment by making medications working better

Do I inject Trigger Shots myself?

In many cases, patients are required to administer the trigger shot themselves. Your fertility clinic will provide detailed instructions on how to properly use the injection, including the correct dosage and technique. If you’re unsure or uncomfortable with self-injection, your healthcare provider can offer additional support.

Where Is the Trigger Shot Typically Given?

The trigger shot is usually administered as an intramuscular injection in the buttocks or thigh. In some cases, it may be given as a subcutaneous injection in the abdomen, depending on the medication and specific instructions from your healthcare provider.

Is the Trigger Injection Painful?

The trigger injection may cause some mild discomfort, similar to a minor pinch or ant stinging sensation. Some individuals may experience burning sensation or itching at the injection site, but it disappears quickly. This discomfort compared to the routine vaccination or blood test. Overall, the pain is minimal and temporary.

I have missed my Trigger Shot. What should I do?

If you miss your trigger shot, it’s crucial to contact your fertility clinic immediately. Missing the shot can affect the timing of egg retrieval and the overall success of your IVF cycle. Your clinic will provide guidance on the next steps and may reschedule your procedures if necessary.

The Chances of Getting Pregnant with a Trigger Shot?

With a trigger shot, the chances of getting pregnant are increased to 18.2%, which is different from the pregnancy rate without a trigger shot that was only 5.8 percent. However, the success of pregnancy with a trigger shot depends on other factors, including health conditions of individuals, age factor, quality of eggs, and how it goes in response to medicines.

How Should Patients Prepare and Manage Side Effects for the Trigger Shot?

Preparation for the trigger shot includes following your clinic’s instructions carefully and being aware of potential side effects, such as bloating, mood swings, or mild pain at the injection site. Managing side effects involves staying hydrated, maintaining a healthy diet, and contacting your healthcare provider if you experience severe or persistent symptoms.

Conclusion

The IVF trigger injection is a crucial step in the fertility process, stimulating ovulation and finalising egg maturation. Precise timing is key, and this injection optimises egg retrieval and fertilisation chances. It sets the stage for successful embryo development, bringing hope to those building their families. The IVF trigger injection is a vital component of modern fertility treatment. It helps patients take a significant step towards parenthood.

FAQs

How long after the trigger shot is egg retrieval?

It typically occurs after 34-36 hours after the trigger shot which enhances the egg maturation and ovulation.

Can I exercise after receiving the trigger injection?

It’s generally advisable to avoid heavy physical activities for 2-3 days after receiving the trigger injection

What if I miss the timing for my trigger shot?

If you miss the timing for trigger shot, it may potentially reduce the chances of successful fertilisation and embryo development.

How do I know if the trigger injection worked?

If your healthcare provider confirms egg maturation and ovulation through ultrasound or blood tests.

How Long Does the Trigger Shot Stay in Your System?​

Following the administration of the trigger shot, hCG remains in the system for approximately 10-14 days. hCG levels surge to peak within the first few hours, then gradually decline as the hormone is metabolised and eliminated by the body. The exact duration can vary depending on the individual factors such as dosage, metabolism rate and overall health of an individual.

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Dr Niveditha

Dr. Niveditha is the co-founder of The Hive Fertility and Research Centre. She is a young and passionate fertility expert who aims to provide high-quality fertility treatments to her patients. During her 10+ years of service as a fertility expert, she has helped several hundreds of patients overcome their infertility and become parents. She also specializes in the fields of obstetrics, gynecology, and reproductive endocrinology

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